I Told You So
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A user mentioned sharing a quote from a study about the Endocannabinoid System and its role in anxiety and depression. The study found the effectiveness of cannabinoid compounds to be comparable to known antidepressants, but only at a low dosage. It was suggested that taking too much could potentially increase feelings of depression and anxiety. The user contemplates collecting all the relevant scientific research, with the intention of presenting it to the local legislature in an attempt to push for the legalization of medical marijuana, arguing that not everyone can tolerate traditional pain medications like opiates.
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The article raises some concerns, particularly the part where it says, "Cannabidiol's biological activities are due to either its inhibition of anandamide degradation, its antioxidant attributes, or its interaction with as yet unidentified cannabinoid receptors". This statement prompts further research because it doesn't fully align with my understanding. Other sources suggest cannabidiol has a higher affinity for CB2 than CB1 receptors.
There's a lot of conflicting information out there, with some sources claiming cannabidiol acts as an antagonist, while others suggest it has agonist activity on CB2. It's a complicated field, and the accurate interpretation is still uncertain due to government restrictions on research and biochemistry that keep us in the dark.
Cannabidiol is primarily active in CB2 as a negative allosteric modulator, a CB2 Antagonist. Its metabolism boosts intracellular enzymes (Epoxides and Fatty acid binding proteins) that help degrade the lipid through lipid signalling. With sufficient cannabidiol in the system, it can communicate with CB1 receptors through lipid rafts and Cytokines.
The metabolism of phytocannabinoids is non-selective, unlike endocannabinoids which are selective and can choose for CB receptors. The medical biochemistry resource is close to explaining this, but not perfect.
Another factor that's not typically considered in cannabidiol research is Chirality! Cannabidiol can dock into CB receptors in about four different ways depending on how it expresses when interacting with the CB receptors. As a three-dimensional shape, the four sides are slightly different.
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The growth of new brain cells is stimulated by cannabis...
Cannabinoids and their role in neurogenesis: Could they be the answer to neurodegeneration?haha
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Cannabidiol helps to reduce depressive symptoms by regulating the differentiation of neural stem cells.
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A while ago, when the Document was only about 500 pages long, an individual printed it all out and displayed it to all at a local festival. The sound it made when he placed it on a table was quite substantial, and it certainly got people's attention, showing them that there are numerous researches conducted on cannabis.
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The text suggests that cannabis can promote hair regrowth more effectively than current medical treatments. It refers to a study where a unique hemp extract was used for hair regrowth, showing significant results within half a year. This treatment seems to be efficient for both men and women, even those who were previously bald. The text also humorously suggests using hair from various body parts, such as ears, eyebrows, and nose, for hair transplantation due to their rapid growth.
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The mentor enthusiastically declared, "@Storm Crow, you are the expert!"
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@Storm Crow, my guide has acknowledged your expertise!
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Your contribution is vital in achieving remarkable outcomes. My presence, however, may not yield positive results. I'm quite outspoken, which is why my children think I'm losing my memory, because I don't censor my speech. I've come to realise that the support I had as a child is no longer there. I've been too passive all my life and I'm tired of it. I should have stood up for myself from the beginning. I blame myself for trusting my children when they told me I could use one of their cars, as they didn't have space for a third vehicle. However, I now realise that I need to get a third car, as my daughter will start driving next year. She plans to use the Camry Hybrid for her commute to university. She also believes that her aunt will allow her to move in, which is amusing. My other daughter has explicitly stated that she doesn't want to share her living space. Even though both my children are university graduates, they still manage to cause me distress and disappointment in other ways.
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Cannabidiol helps in mitigating depressive tendencies by regulating the differentiation of neural stem cells.
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The post asserts that cannabis has a superior effect in promoting hair regrowth compared to contemporary medicine. The evidence presented involves a case series of successful hair regrowth using a unique hemp extract, particularly noteworthy in a previously bald man within a span of six months. The results are not limited to men but also extend to women. The poster humorously suggests a solution to baldness could be transplanting hair from areas like the ears, eyebrows, and nose, as those regions seem to have a rapid hair growth rate.
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The user shared an interesting discovery that cannabis can promote hair regrowth more effectively than contemporary medical treatments. They mentioned a case study about hair regrowth using a unique hemp extract, showing impressive results within just six months. This treatment seems to work not only for men but also for women. The user jokingly clarified that they aren't the individual in the pictures, and they've shared the information with their daughter, whose husband is experiencing hair loss.
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The growth of new brain cells is promoted by cannabinoids... Could this be the long-awaited answer to neurodegeneration?
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Here's a speedy connection to a page that provides information about Cannabinoids, explaining their biochemical processes. It focuses on endocannabinoids and their role in feeding behaviour and maintaining energy balance.
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Is the reason I consistently overlooked my anti-depressant medication due to my CBD gummy intake? I stumbled upon some information recently and wanted to share it here as well, so as not to misguide anyone.
This information was derived from a study regarding the Endocannabinoid System and its relation to depression and anxiety when influenced by external cannabinoids.
The study found that the effectiveness of these cannabinoid substances was on par with certain recognized antidepressants. Mostly, these beneficial impacts on depression and anxiety were noted at relatively lower doses of cannabinoids which activated CB1R. Conversely, higher doses often resulted in increased depression and anxiety.
Just as the proverb goes, moderation is key.
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The mentor voiced their admiration for Storm Crow, declaring them to be an expert.
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Hemp extract aids in hair regrowth, surpassing the capabilities of contemporary medical treatments.
Hair Regrowth through Innovative Hemp Extract: A Collection of Cases
Impressive results observed in just half a year, even for a previously bald individual! It's effective for females as well. A clarification - the subject in question isn't me.
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Cannabidiol helps in reducing symptoms of depression by influencing the differentiation of neural stem cells, thereby preventing behaviours associated with depression.
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The user was perusing an article, which he found to be quite extensive, and came across a statement that piqued his interest. It stated that cannabidiol doesn't interact much with CB1 or CB2 receptors, and its biological functions are attributed to either the inhibition of anandamide degradation, its antioxidant characteristics, or its interaction with unrecognised cannabinoid receptors. This statement caused him some confusion, prompting him to delve deeper into the issue. He found conflicting information in various sources indicating the activity of cannabidiol.
He also found disagreement on whether cannabidiol serves as an antagonist or an agonist on CB2. The intricacies of these interactions are still unresolved, partly due to government restrictions on research in this area.
It is understood that cannabidiol primarily acts on CB2 as a negative allosteric modulator, and as a CB2 antagonist. Its metabolism triggers intracellular enzymes that lead to the breakdown of lipids. If there is a sufficient amount of cannabidiol, it can communicate with CB1 through lipid rafts and cytokines.
The metabolism of phytocannabinoids is non-selective, unlike endocannabinoids which are selective and can choose CB receptors. The user also points out that the chirality of cannabidiol, an aspect often overlooked in research, allows it to connect with CB receptors in numerous ways, depending on how it interacts with the receptors.
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I appreciate the information. I'm genuinely considering collecting all the relevant scientific findings I can get my hands on, hiring a van, and delivering them to the local government in Melbourne. Then I could present them with the research they've been asking for. With this, they should at least allow for medical use, as some individuals can't tolerate opiate-based painkillers. Achieving such significant milestones requires individuals like yourself. However, my presence there might not be the best idea.